Last update 22 Dec 2024

RDEA-427

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
RDEA 427, RDEA427
Target
RT
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesUrogenital Diseases
Active Indication-
Inactive Indication
HIV Infections
Originator Organization
Bausch Health Cos., Inc.Bausch Health Cos., Inc.
Active Organization-
Inactive Organization
Ardea Biosciences, Inc.Ardea Biosciences, Inc.Bausch Health Cos., Inc.Bausch Health Cos., Inc.AstraZeneca Pharmaceuticals Co. Ltd.AstraZeneca Pharmaceuticals Co. Ltd.
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Structure

Molecular FormulaC22H16N6O
InChIKeyPFGKQRWHIVJCSQ-UHFFFAOYSA-N
CAS Registry914496-19-8

Related

100 Clinical Results associated with RDEA-427
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100 Translational Medicine associated with RDEA-427
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100 Patents (Medical) associated with RDEA-427
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1
Literatures (Medical) associated with RDEA-427
01 May 2018Bioorganic & medicinal chemistry lettersQ4 · MEDICINE
First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strain
Q4 · MEDICINE
100 Deals associated with RDEA-427
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 1
US
Ardea Biosciences, Inc.Ardea Biosciences, Inc.
-
HIV InfectionsPhase 1-
Bausch Health Cos., Inc.Bausch Health Cos., Inc.
-
HIV InfectionsPhase 1-
AstraZeneca Pharmaceuticals Co. Ltd.AstraZeneca Pharmaceuticals Co. Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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