Last update 10 May 2025

LF0397

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
LF 0397, LF-0397, LF0397
Target
ATR
Action
inhibitors
Mechanism
ATR inhibitors(Serine-protein kinase ATR inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
Advanced Malignant Solid NeoplasmLymphoma
Inactive Indication-
Originator Organization
Shenzhen Lingfang Biomedical Technology Co., Ltd.Shenzhen Lingfang Biomedical Technology Co., Ltd.
Active Organization
Shenzhen Lingfang Biomedical Technology Co., Ltd.Shenzhen Lingfang Biomedical Technology Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with LF0397
CTR20221402
/ RecruitingPhase 1
评价LF0397片在晚期实体瘤患者中的安全性、耐受性、药代动力学特征及初步有效性的开放、多中心、Ia期临床试验
[Translation] An open, multicenter, Phase Ia clinical trial to evaluate the safety, tolerability, pharmacokinetic characteristics and preliminary efficacy of LF0397 tablets in patients with advanced solid tumors
100 Clinical Results associated with LF0397
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100 Translational Medicine associated with LF0397
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100 Patents (Medical) associated with LF0397
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100 Deals associated with LF0397
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
China
Shenzhen Lingfang Biomedical Technology Co., Ltd.Shenzhen Lingfang Biomedical Technology Co., Ltd.
30 Jun 2022
LymphomaIND Approval
China
Shenzhen Lingfang Biomedical Technology Co., Ltd.Shenzhen Lingfang Biomedical Technology Co., Ltd.
19 Feb 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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