Last update 21 Nov 2024

177Lu-capromab pendetide(Jazz Pharmaceuticals Plc)

Overview

Basic Info

Drug Type
Radiolabeled antibody, Therapeutic radiopharmaceuticals
Synonyms
7E11-C5.3-meO- DOTA-177Lu, Anti-PSMA-meO-DOTA-177Lu
+ [2]
Target
PSMA
Mechanism
PSMA inhibitors(Prostate-specific membrane antigen inhibitors), Ionising radiation emitters
Therapeutic Areas
NeoplasmsUrogenital Diseases
Active Indication-
Inactive Indication
Castration-Resistant Prostatic CancerMetastatic Prostate Carcinoma
Originator Organization
Jazz Pharmaceuticals Plc
Active Organization-
Inactive Organization
Jazz Pharmaceuticals (EUSA Pharma USA), Inc.Jazz Pharmaceuticals (EUSA Pharma USA), Inc.
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Structure

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Related

1
Clinical Trials associated with 177Lu-capromab pendetide(Jazz Pharmaceuticals Plc)
NCT00441571 / Unknown statusPhase 1
A Phase 1 Study of Radiolabeled Monoclonal Antibody 7E11-C5.3(177Lu-meO-DOTA-7E11;CYT-500) in Patients With Progressive Androgen-Independent Prostate Cancer
100 Clinical Results associated with 177Lu-capromab pendetide(Jazz Pharmaceuticals Plc)
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100 Translational Medicine associated with 177Lu-capromab pendetide(Jazz Pharmaceuticals Plc)
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100 Patents (Medical) associated with 177Lu-capromab pendetide(Jazz Pharmaceuticals Plc)
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1
Literatures (Medical) associated with 177Lu-capromab pendetide(Jazz Pharmaceuticals Plc)
Scientific Reports
Determination of pharmacokinetics and tissue distribution of a novel lutetium-labeled PSMA-targeted ligand, 177Lu-DOTA-PSMA-GUL, in rats by using LC–MS/MS
100 Deals associated with 177Lu-capromab pendetide(Jazz Pharmaceuticals Plc)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Castration-Resistant Prostatic CancerPhase 1
US
Jazz Pharmaceuticals (EUSA Pharma USA), Inc.Jazz Pharmaceuticals (EUSA Pharma USA), Inc.
01 Feb 2007
Metastatic Prostate CarcinomaPhase 1
US
Jazz Pharmaceuticals (EUSA Pharma USA), Inc.Jazz Pharmaceuticals (EUSA Pharma USA), Inc.
01 Feb 2007
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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