[Translation] A Phase I clinical study to evaluate the safety, tolerability, pharmacokinetics and food effects of single and multiple doses of GST-HG121 tablets in healthy adult Chinese subjects.
主要目的
1.评价成年健康受试者单次、多次服用GST-HG121片后的安全性和耐受性;
次要目的
1.评价成年健康受试者单次、多次服用GST-HG121片后的药代动力学特征;
2.评价食物对GST-HG121片药代动力学特征的影响;
3.初步探索GST-HG121片的药物代谢转化。
[Translation] Main purpose
1. To evaluate the safety and tolerability of GST-HG121 tablets after single and multiple administrations in healthy adult subjects;
Secondary purpose
1. To evaluate the pharmacokinetic characteristics of GST-HG121 tablets after single and multiple administrations in healthy adult subjects;
2. To evaluate the effect of food on the pharmacokinetic characteristics of GST-HG121 tablets;
3. To preliminarily explore the drug metabolism transformation of GST-HG121 tablets.