Last update 22 Dec 2024

PHA665752-based degraders 8(Dana-Farber Cancer Institute)

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms-
Target
c-Met
Mechanism
c-Met inhibitors(Hepatocyte growth factor receptor inhibitors)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Leukemia
Inactive Indication-
Originator Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.
Active Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure

Molecular FormulaC42H40Cl2N6O8S
InChIKeyQPKXJIBPFUZACW-RRAHZORUSA-N
CAS Registry2222635-85-8

Related

100 Clinical Results associated with PHA665752-based degraders 8(Dana-Farber Cancer Institute)
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100 Translational Medicine associated with PHA665752-based degraders 8(Dana-Farber Cancer Institute)
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100 Patents (Medical) associated with PHA665752-based degraders 8(Dana-Farber Cancer Institute)
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100 Deals associated with PHA665752-based degraders 8(Dana-Farber Cancer Institute)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
LeukemiaPreclinical
US
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
22 Jan 2018
LeukemiaPreclinical
US
Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.
22 Jan 2018
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Approval

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Regulation

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