Last update 07 Jun 2025

RNA CART-cMET(University of Pennsylvania)

Overview

Basic Info

Drug Type
CAR-T
Synonyms
cMet CAR RNA T Cells(University of Pennsylvania)
Target
HGF
Action
modulators, stimulants
Mechanism
HGF modulators(Hepatocyte growth factor modulators), T lymphocytes stimulants
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication-
Inactive Indication
MelanomaMetastatic breast cancerTriple Negative Breast Cancer
Originator Organization
University of PennsylvaniaUniversity of Pennsylvania
Active Organization-
Inactive Organization
University of PennsylvaniaUniversity of Pennsylvania
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with RNA CART-cMET(University of Pennsylvania)
NCT03060356
/ TerminatedEarly Phase 1IIT
Clinical Trial of Autologous cMET Redirected T Cells Administered Intravenously in Patients With Melanoma & Breast Carcinoma
NCT01837602
/ CompletedPhase 1IIT
Clinical Trial of Autologous cMet Redirected T Cells Administered Intratumorally in Patients With Breast Cancer
100 Clinical Results associated with RNA CART-cMET(University of Pennsylvania)
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100 Translational Medicine associated with RNA CART-cMET(University of Pennsylvania)
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100 Patents (Medical) associated with RNA CART-cMET(University of Pennsylvania)
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100 Deals associated with RNA CART-cMET(University of Pennsylvania)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MelanomaPhase 1
United States
University of PennsylvaniaUniversity of Pennsylvania
21 Dec 2016
Metastatic breast cancerPhase 1
United States
University of PennsylvaniaUniversity of Pennsylvania
01 Apr 2013
Triple Negative Breast CancerPhase 1
United States
University of PennsylvaniaUniversity of Pennsylvania
01 Apr 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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