Last update 16 Jul 2025

HBL-5

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
HBL-5
Target
BRD4 x PLK1
Action
degraders
Mechanism
BRD4 degraders(Bromodomain-containing protein 4 degraders), PLK1 degraders(Polo like kinase 1 degraders), Epigenetic drug
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Acute Myeloid Leukemia
Inactive Indication-
Originator Organization
Jilin UniversityJilin University
Active Organization
Jilin UniversityJilin University
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC45H57N9O11
InChIKeyGLNZQWXKBMEKNA-BONSOQDYSA-N
CAS Registry2890766-69-3

Related

100 Clinical Results associated with HBL-5
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100 Translational Medicine associated with HBL-5
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100 Patents (Medical) associated with HBL-5
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100 Deals associated with HBL-5
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPreclinical
China
Jilin UniversityJilin University
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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