[Translation] A single-center, randomized, double-blind, placebo-controlled, dose-escalation Phase I clinical study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of a single dose of VSA012 injection in healthy adult volunteers in China
主要目的:
在健康受试者中评价 VSA012 单次皮下注射给药的安全性和耐受性。
次要目的:
在健康受试者中评价 VSA012 单次皮下注射给药后,血浆中VSA012 的药代动力学(PK)、血清中VSA012的药效学(PD)及免疫原性特征。
[Translation] Primary objective:
To evaluate the safety and tolerability of a single subcutaneous injection of VSA012 in healthy subjects.
Secondary objective:
To evaluate the pharmacokinetics (PK) of VSA012 in plasma, the pharmacodynamics (PD) of VSA012 in serum and the immunogenicity characteristics of VSA012 after a single subcutaneous injection of VSA012 in healthy subjects.