Last update 08 May 2025

D-228

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
MYD88 x TRAF6 x p38 MAPK
Action
inhibitors, antagonists
Mechanism
MYD88 inhibitors(MYD88 innate immune signal transduction adaptor inhibitors), TRAF6 antagonists(TNF receptor associated factor 6 antagonists), p38 MAPK inhibitors(P38 mitogen-activated protein kinase inhibitors)
Therapeutic Areas
Immune System DiseasesDigestive System Disorders
Active Indication
Inflammatory Bowel Diseases
Inactive Indication-
Originator Organization
Fudan UniversityFudan University
Active Organization
Fudan UniversityFudan University
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with D-228
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100 Translational Medicine associated with D-228
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100 Patents (Medical) associated with D-228
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1
Literatures (Medical) associated with D-228
10 Oct 2024Journal of Medicinal Chemistry
From Hit to Lead: Discovery of First-In-Class Furanone Glycoside D228 Derived from Chimonanthus salicifolius for the Treatment of Inflammatory Bowel Disease
100 Deals associated with D-228
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Inflammatory Bowel DiseasesPreclinical
United States
Fudan UniversityFudan University
19 Sep 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Clinical Trial

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Approval

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Regulation

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