Last update 27 Aug 2026

LW-231

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
LW 231, LW231
Target
HBV capsid
Action
inhibitors
Mechanism
HBV capsid inhibitors(HBV capsid inhibitors)
Therapeutic Areas
Infectious DiseasesDigestive System Disorders
Active Indication
Hepatitis B, Chronic
Inactive Indication-
Originator Organization
Shanghai Changsen Pharmaceutical Co., Ltd.Shanghai Changsen Pharmaceutical Co., Ltd.
Active Organization
Shanghai Changsen Pharmaceutical Co., Ltd.Shanghai Changsen Pharmaceutical Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

4
Clinical Trials associated with LW-231
NCT07179575
/ RecruitingPhase 1/2
Phase Ib/II Study of LW231 in Patients With Chronic Hepatitis B: Evaluation of Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy With Multiple-Dose, Dose-Escalation, and Combination With Nucleos(t)Ide Analogs (NUC)
ChiCTR2600123516
/ RecruitingPhase 1/2IIT
Evaluation of the Phase Ib/II Clinical Trial Investigating the Safety, Tolerability, Pharmacokinetics, Preliminary Efficacy, and Pharmacodynamics of Multiple Ascending Doses of LW231 and LW231 in Combination with Nucleos(t)ide Analogues in Patients with Chronic Hepatitis B Virus (HBV) Infection
NCT06311734
/ CompletedPhase 1
A Single-center, Randomized, Double-blind,Placebo-controlled Study, to Evaluate Safety,Tolerability, Pharmacokinetics and Pharmacodynamics of LW231 in Healthy Volunteers and Patients With Chronic Hepatitis B Virus Infection
100 Clinical Results associated with LW-231
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100 Translational Medicine associated with LW-231
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100 Patents (Medical) associated with LW-231
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100 Deals associated with LW-231
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis B, ChronicPhase 2
China
Shanghai Changsen Pharmaceutical Co., Ltd.Shanghai Changsen Pharmaceutical Co., Ltd.
11 Nov 2025
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Clinical Trial

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Approval

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Regulation

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