Last update 16 May 2025

C-21-7D12

Overview

Basic Info

Drug Type
Bispecific killer cell engager (BiKE)
Synonyms
C-7 biVHH, C-21-7D12
Target
CD16a x EGFR
Action
agonists, modulators
Mechanism
CD16a agonists(Low affinity immunoglobulin gamma Fc region receptor III-A agonists), EGFR modulators(Epidermal growth factor receptor erbB1 modulators)
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication
Colorectal Cancer
Inactive Indication-
Originator Organization
Vrije Universiteit AmsterdamVrije Universiteit Amsterdam
Active Organization
Vrije Universiteit AmsterdamVrije Universiteit AmsterdamGlycostem BV
Radboud Institute for Health Sciences
+ [1]
Inactive Organization-
License Organization-
Drug Highest PhaseDiscovery
First Approval Date-
Regulation-

Related

100 Clinical Results associated with C-21-7D12
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100 Translational Medicine associated with C-21-7D12
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100 Patents (Medical) associated with C-21-7D12
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100 Deals associated with C-21-7D12
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colorectal CancerDiscovery
Netherlands
Vrije Universiteit AmsterdamVrije Universiteit Amsterdam
-
Colorectal CancerDiscovery
Netherlands
Glycostem BV
-
Colorectal CancerDiscovery
Netherlands
Radboud Institute for Health Sciences
-
Colorectal CancerDiscovery
Netherlands
LAVA Therapeutics NVLAVA Therapeutics NV
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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