[Translation] A randomized, double-blind, placebo-controlled Phase I clinical study to evaluate the safety, tolerability, and pharmacokinetics of MWX203 injection after a single subcutaneous administration in healthy Chinese subjects
主要目的:
1、评估MWX203注射液在中国健康受试者中单次给药的安全性、耐受性。
次要目的:
1、评估 MWX203 注射液在中国健康受试者中单次给药的药代动力学;
2、评估 MWX203 在中国健康受试者中单次给药的免疫原性。
探索性目的:
1、评估 MWX203 注射液在中国健康受试者中单次给药的药效学;
2、评估 MWX203 可能的代谢产物。
[Translation] Primary objectives:
1. To evaluate the safety and tolerability of a single dose of MWX203 injection in healthy Chinese subjects.
Secondary objectives:
1. To evaluate the pharmacokinetics of a single dose of MWX203 injection in healthy Chinese subjects;
2. To evaluate the immunogenicity of a single dose of MWX203 in healthy Chinese subjects.
Exploratory objectives:
1. To evaluate the pharmacodynamics of a single dose of MWX203 injection in healthy Chinese subjects;
2. To evaluate the possible metabolites of MWX203.