Last update 20 Mar 2025

MDX-240

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
Anti-gp41-anti-Fc monoclonal antibody
Target
CD64 x gp41
Action
antagonists, inhibitors
Mechanism
CD64 antagonists(High affinity immunoglobulin gamma Fc receptor I antagonists), gp41 inhibitors(Transmembrane glycoprotein gp41 inhibitors)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesUrogenital Diseases
Active Indication-
Inactive Indication
HIV Infections
Originator Organization
Medarex, Inc.Medarex, Inc.
Active Organization-
Inactive Organization
Medarex, Inc.Medarex, Inc.
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with MDX-240
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100 Translational Medicine associated with MDX-240
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100 Patents (Medical) associated with MDX-240
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1
Literatures (Medical) associated with MDX-240
01 Dec 1995Journal of Hematotherapy
Functional Consequences of Macrophage Infection by Human Immunodeficiency Virus: Bispecific Antibody Targeting of HIV-1-Infected Cells to FcγRI Expressing Effector Cells
100 Deals associated with MDX-240
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 2
France
Medarex, Inc.Medarex, Inc.
-
HIV InfectionsPhase 2
Belgium
Medarex, Inc.Medarex, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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