Last update 24 Oct 2025

HP-537

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
HP 537, HP-537, HP537
Target
p300-CBP transcription factors
Action
inhibitors
Mechanism
p300-CBP transcription factors inhibitors
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [2]
Active Indication
Acute Myeloid LeukemiaMultiple MyelomaMyelodysplastic Syndromes+ [3]
Inactive Indication-
Originator Organization
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
Active Organization
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals (Usa) Inc
Inactive Organization-
License Organization-
Drug Highest PhaseIND Approval
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with HP-537
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100 Translational Medicine associated with HP-537
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100 Patents (Medical) associated with HP-537
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100 Deals associated with HP-537
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaIND Approval
China
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
22 Feb 2024
Multiple MyelomaIND Approval
China
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
22 Feb 2024
Myelodysplastic SyndromesIND Approval
China
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
22 Feb 2024
Hematologic NeoplasmsIND Application
United States
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
01 Jun 2025
Breast CancerPreclinical
China
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
-
Prostatic CancerPreclinical
China
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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