Drug Type Small molecule drug |
Synonyms 1,2,3,4-tetrahydro-9-acridinamine, 1,2,3,4-tetrahydro-9-aminoacridine, 1,2,3,4-tetrahydroacridin-9-amine + [13] |
Target |
Mechanism AChE inhibitors(Acetylcholinesterase inhibitors), Cholinesterase inhibitors |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseWithdrawn |
First Approval Date US (09 Sep 1993), |
Regulation- |
Molecular FormulaC13H15ClN2 |
InChIKeyZUFVXZVXEJHHBN-UHFFFAOYSA-N |
CAS Registry1684-40-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D02068 | Tacrine Hydrochloride |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Alzheimer Disease | US | 09 Sep 1993 |
Not Applicable | - | - | kvbyaolozg(ydlidtczlr) = Tacrine was the first acetylcholinesterase inhibitor approved for therapy of Alzheimer’s disease. Tacrine has dose-limiting side effects, including diarrhoea, nausea, vomiting and abdominal discomfort. ibhmcipzvd (bgfgpdtumw ) View more | - | 01 Oct 2015 | ||