Last update 08 May 2025

14C-labeled poziotinib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target-
Action
inhibitors
Mechanism
EGFR exon 20 inhibitors(EGFR exon 20 Mutation inhibitors), HER2 exon 20 inhibitors(ERBB2 Exon 20 Mutation inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Solid tumor
Originator Organization
Spectrum Pharmaceuticals, Inc.Spectrum Pharmaceuticals, Inc.
Active Organization-
Inactive Organization
Spectrum Pharmaceuticals, Inc.Spectrum Pharmaceuticals, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

3
Clinical Trials associated with 14C-labeled poziotinib
NCT04436562
/ CompletedPhase 1
Phase 1 Open-label Study of the Absorption, Metabolism, and Excretion of Poziotinib Following a Single Oral Dose of [14C]-Poziotinib in Healthy Male Subjects
NCT03804515
/ TerminatedPhase 1
A Phase 1 Study for the Evaluation of Excretion (Mass Balance) and Pharmacokinetics of 14C-Labeled Poziotinib in Cancer Patients Suitable for Treatment With Poziotinib
NCT02418689
/ CompletedPhase 2
A Prospective, Open-label, Single-arm, Multi-Center, Phase II Trial of NOV120101 in Patients With HER2-overexpressed Recurrent Stage IV Breast Cancer Who Have Received at Least 2 Prior HER2-directed Regimens
100 Clinical Results associated with 14C-labeled poziotinib
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100 Translational Medicine associated with 14C-labeled poziotinib
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100 Patents (Medical) associated with 14C-labeled poziotinib
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100 Deals associated with 14C-labeled poziotinib
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPhase 1
United States
Spectrum Pharmaceuticals, Inc.Spectrum Pharmaceuticals, Inc.
25 Jun 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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