Last update 26 Jun 2024

Hydrochlorothiazide/Dihydralazine Sulfate/Promethazine Hydrochloride/Rutin/Chloroquine Phosphate/Potassium Chloride/Pyridoxine Hydrochloride/Thiamine Hydrochloride/Reserpine/Magnesium Trisilicate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Compound Trizin and Rutinum, Hydrochlorothiazide/Dihydralazine Sulfate/Promethazine Hydrochloride/Rutin/Chloroquine phosphate/Potassium Chloride/Vitamin B6/V/itamin B1/Reserpine/Magnesium Trisilicate, 复方三嗪芦丁
Target
H1 receptor x NCC x VMAT1 x VMAT2
Mechanism
H1 receptor antagonists(Histamine H1 receptor antagonists), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors), VMAT1 antagonists(solute carrier family 18 member A1 antagonists)
Therapeutic Areas
Cardiovascular Diseases
Active Indication
Hypertension
Inactive Indication-
Originator Organization-
Active Organization-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date-
Regulation-

Structure

Molecular FormulaC18H29ClN3O4P
InChIKeyAEUAEICGCMSYCQ-UHFFFAOYSA-N
CAS Registry50-63-5
View All Structures (9)

Related

100 Clinical Results associated with Hydrochlorothiazide/Dihydralazine Sulfate/Promethazine Hydrochloride/Rutin/Chloroquine Phosphate/Potassium Chloride/Pyridoxine Hydrochloride/Thiamine Hydrochloride/Reserpine/Magnesium Trisilicate
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100 Translational Medicine associated with Hydrochlorothiazide/Dihydralazine Sulfate/Promethazine Hydrochloride/Rutin/Chloroquine Phosphate/Potassium Chloride/Pyridoxine Hydrochloride/Thiamine Hydrochloride/Reserpine/Magnesium Trisilicate
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100 Patents (Medical) associated with Hydrochlorothiazide/Dihydralazine Sulfate/Promethazine Hydrochloride/Rutin/Chloroquine Phosphate/Potassium Chloride/Pyridoxine Hydrochloride/Thiamine Hydrochloride/Reserpine/Magnesium Trisilicate
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100 Deals associated with Hydrochlorothiazide/Dihydralazine Sulfate/Promethazine Hydrochloride/Rutin/Chloroquine Phosphate/Potassium Chloride/Pyridoxine Hydrochloride/Thiamine Hydrochloride/Reserpine/Magnesium Trisilicate
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
CN
--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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