Last update 17 Jan 2025

Hydrochlorothiazide/Dihydralazine Sulfate/Promethazine Hydrochloride/Rutin/Chloroquine Phosphate/Potassium Chloride/Pyridoxine Hydrochloride/Thiamine Hydrochloride/Reserpine/Magnesium Trisilicate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Compound Trizin and Rutinum, 复方三嗪芦丁
Target
H1 receptor x NCC x VMAT1 x VMAT2
Mechanism
H1 receptor antagonists(Histamine H1 receptor antagonists), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors), VMAT1 antagonists(solute carrier family 18 member A1 antagonists)
Therapeutic Areas
Cardiovascular Diseases
Active Indication
Hypertension
Inactive Indication-
Originator Organization-
Active Organization
Shenyang Oasis Pharmaceutical Co., LtdShenyang Oasis Pharmaceutical Co., Ltd
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC18H29ClN3O4P
InChIKeyAEUAEICGCMSYCQ-UHFFFAOYSA-N
CAS Registry50-63-5
View All Structures (10)

Related

100 Clinical Results associated with Hydrochlorothiazide/Dihydralazine Sulfate/Promethazine Hydrochloride/Rutin/Chloroquine Phosphate/Potassium Chloride/Pyridoxine Hydrochloride/Thiamine Hydrochloride/Reserpine/Magnesium Trisilicate
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100 Translational Medicine associated with Hydrochlorothiazide/Dihydralazine Sulfate/Promethazine Hydrochloride/Rutin/Chloroquine Phosphate/Potassium Chloride/Pyridoxine Hydrochloride/Thiamine Hydrochloride/Reserpine/Magnesium Trisilicate
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100 Patents (Medical) associated with Hydrochlorothiazide/Dihydralazine Sulfate/Promethazine Hydrochloride/Rutin/Chloroquine Phosphate/Potassium Chloride/Pyridoxine Hydrochloride/Thiamine Hydrochloride/Reserpine/Magnesium Trisilicate
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100 Deals associated with Hydrochlorothiazide/Dihydralazine Sulfate/Promethazine Hydrochloride/Rutin/Chloroquine Phosphate/Potassium Chloride/Pyridoxine Hydrochloride/Thiamine Hydrochloride/Reserpine/Magnesium Trisilicate
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
CN
Shenyang Oasis Pharmaceutical Co., LtdShenyang Oasis Pharmaceutical Co., Ltd
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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