[Translation] A randomized double-blind parallel controlled clinical trial of refined gynecological Qianjin tablets in the treatment of leucorrhea (chronic pelvic inflammatory disease, chronic cervicitis) of damp-heat stasis and qi-blood deficiency type

按《药品注册管理办法》之补充申请要求，以原妇科千金片（一次6片）为阳性对照，评价精制妇科千金片（一次3片）治疗湿热瘀阻兼气血不足型慢性盆腔炎含子宫内膜炎、慢性宫颈炎的有效性和安全性。

[Translation]

According to the supplementary application requirements of the "Drug Registration Management Measures", the original Fuke Qianjin Tablets (6 tablets at a time) were used as the positive control to evaluate the effectiveness and safety of the refined Fuke Qianjin Tablets (3 tablets at a time) in the treatment of chronic pelvic inflammatory disease (including endometritis and chronic cervicitis) of damp-heat and blood stasis and qi and blood deficiency.

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100 Clinical Results associated with Fuke Qianjin Tablets

100 Translational Medicine associated with Fuke Qianjin Tablets

100 Patents (Medical) associated with Fuke Qianjin Tablets

Literatures (Medical) associated with Fuke Qianjin Tablets

07 Jul 2023·Medicine

The efficacy of Fuke Qianjin tablets combined with clomiphene citrate on infertility patients with polycystic ovary syndrome: A retrospective analysis

Article

Author: Li, Li-Hui ; Ge, Xin ; Zhang, Yu ; Hu, Shu-Hong ; Liang, Jun-Xia ; Cao, Shan ; Li, Ya-Xue

Purpose:Clinical efficacy of Fuke Qianjin tablets combined with clomiphene citrate on infertility patients with polycystic ovary syndrome (PCOS) was expected to be retrospectively analyzed in this study.Methods:In this paper, 100 infertility patients with PCOS were selected and divided into the observation and control groups based on different medications. Firstly, clinical data of both groups of patients were acquired. Then, the uterine receptivity and ovarian status, the levels of sex hormones, inflammation and oxidative stress, and the pregnancy outcomes between the 2 groups were compared and analyzed before and after treatment.Results:After a variety of comparisons and analyses, Fuke Qianjin tablets combined with clomiphene citrate were confirmed to improve the uterine receptivity and ovarian status, levels of sex hormone, inflammation and oxidative stress, and pregnancy outcomes in infertility patients with PCOS.Conclusions:Overall, Fuke Qianjin tablets + clomiphene citrate treatment shows good clinical efficacy and is worth promotion in clinical practice.

17 Feb 2021·Evidence-Based Complementary and Alternative MedicineQ4 · MEDICINE

Systematic Review and Meta-Analysis of Randomized Controlled Trials of Fuke Qianjin Tablet

Q4 · MEDICINE

ArticleOA

Author: Meng-Pei, Zhang ; Xiao-Mei, Wang ; Kai-Ni, Zuo ; Jie, Pan ; Hao-Xiang, Zhang ; Zhi-Heng, Wang ; Wen-Tao, Zhu

Purpose. The aim of the research was to evaluate the efficacy and safety associated with Fuke Qianjin tablet combined with conventional therapy in the treatment of pelvic inflammatory diseases and associated complications (endometritis) using a meta-analysis approach. Patients and Methods. We searched 8 electronic databases up to December 31, 2019, including PubMed, the Cochrane Library, Embase, Web of Science, CNKI, WanFang, VIP, and SinoMed. Eligible studies were clinical trials of Fuke Qianjin tablet combined with conventional therapy used in the treatment of acute pelvic inflammatory disease, chronic pelvic inflammatory disease, and endometritis. The meta-analysis was performed using STATA15 software. Results. A total of 125 RCTs (n = 14,494) were shortlisted for the meta-analysis, which included 23 trials for acute pelvic inflammatory disease, 69 trials for chronic pelvic inflammatory disease, and 33 trials for endometritis. The overall analysis illustrated Fuke Qianjin tablet combined with conventional therapy was significantly more efficacious than conventional therapy alone across all types of antibiotics treatment for acute pelvic inflammatory disease (OR = 5.57, 95% CI 4.09–7.58, Z = 10.90,

p = 0.001

), chronic pelvic inflammatory disease (OR = 4.70, 95% CI 4.07–5.42, Z = 21.21,

p = 0.001

) and endometritis (OR = 5.09, 95% CI 4.03–6.43; Z = 13.63,

p = 0.001

) in both primary endpoints and secondary endpoints. There is also a trend that Fuke Qianjin tablet combined with conventional therapy has lower adverse reaction rates than conventional therapy alone. Conclusion. Fuke Qianjin tablet combined with conventional therapy showed better clinical efficacy in the treatment of acute pelvic inflammatory disease, chronic pelvic inflammatory disease, and endometritis. There were no obvious drug-related adverse reactions. Fuke Qianjin tablet presented advantages in shortening the remission time of clinical symptoms, reducing the concentration of serum inflammatory factors, improving endometrial thickness, menstruation, and reducing relapse rate.

15 Aug 2016·China Journal of Chinese Materia Medica

Meta-analysis on efficacy of Fuke Qianjin tablets (capsules) combined with antibiotics in treatment of endometritis

Article

Author: Wang, Li ; Xue, Ya-Nan ; Ma, Shu-Yun ; Xu, Rui ; Zhang, Shao-Hua

To systemically evaluate the clinical efficacy of Fuke Qianjin tablets combined with antibiotics in the treatment of endometritis. The databases such as PubMed, CNKI, VIP and WanFang Data were searched to collect the randomized controlled trials(RCTs) about Fuke Qianjin tablets combined with antibiotics for endometritis since 2010. According to the Cochrane Reviewer's Handbook, two reviewers independently screened the literature, extracted the data and assessed the methodological quality of the included studies. Then the Meta-analysis was performed by using RevMan 5.3 software. 16 RCTs were included, involving 2 299 patients. Meta-analysis showed that after endometritis was treated by Fuke Qianjin tablets combined with antibiotics, the thickness of endometrium was higher than that in antibiotics group[MD=1.20, 95％CI (1.10, 1.29), P<0.000 01]; the occurrence rate of normal menstrual cycle[OR=1.46,95％CI (1.21, 1.77), P=0.000 1] and total effective rate [OR=1.19, 95％CI (1.15, 1.24), P<0.000 01] were increased ; the irregular vaginal bleeding [OR=0.21, 95％CI (0.14, 0.30), P<0.000 01] and inflammatory reactions[OR=0.19, 95％CI (0.10, 0.37)] were reduced. In short, Fuke Qianjin tablets combined with antibiotics have better effects than antibiotics alone for endometritis, so it is worthy to be recommended for clinical application.

100 Deals associated with Fuke Qianjin Tablets

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Indication	Country/Location	Organization	Date
Endometritis	CN	Zhuzhou Qianjin Pharmaceutical Co., Ltd.	31 May 2019
Uterine Cervicitis	CN	Zhuzhou Qianjin Pharmaceutical Co., Ltd.	31 May 2019

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