Last update 16 Jul 2025

Folate-MS432

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms-
Target
MEK1 x MEK2
Action
degraders
Mechanism
MEK1 degraders(Dual specificity mitogen-activated protein kinase kinase 1 degraders), MEK2 degraders(Dual specificity mitogen-activated protein kinase kinase 2 degraders), Proteolysis
Therapeutic Areas
Neoplasms
Active Indication
Neoplasms
Inactive Indication-
Originator Organization
Harvard UniversityHarvard University
Active Organization
Harvard UniversityHarvard University
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC77H94F3IN18O12S
InChIKeyXPXBOJCDLYUMCO-WXWGOGOJSA-N
CAS Registry2769735-56-8

Related

100 Clinical Results associated with Folate-MS432
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100 Translational Medicine associated with Folate-MS432
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100 Patents (Medical) associated with Folate-MS432
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100 Deals associated with Folate-MS432
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
Harvard UniversityHarvard University
25 Mar 2022
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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