Last update 01 Nov 2025

AFTX-002

Overview

Basic Info

Drug Type
Gene therapy, DNA encoding mab
Synonyms
Anc 80L65-trastuzumab, AFTX 002, AFTX002
Target
HER2
Action
antagonists
Mechanism
HER2 antagonists(Receptor tyrosine-protein kinase erbB-2 antagonists), Gene transference(Gene transference)
Therapeutic Areas
NeoplasmsNervous System Diseases
Active Indication
Brain metastases
Inactive Indication
Breast Carcinoma Metastatic in the Brain
Originator Organization
Affinia Therapeutics, Inc.Affinia Therapeutics, Inc.
Active Organization
Affinia Therapeutics, Inc.Affinia Therapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with AFTX-002
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100 Translational Medicine associated with AFTX-002
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100 Patents (Medical) associated with AFTX-002
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100 Deals associated with AFTX-002
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Brain metastasesPreclinical
United States
Affinia Therapeutics, Inc.Affinia Therapeutics, Inc.
04 Jan 2022
Breast Carcinoma Metastatic in the BrainPreclinical
United States
Affinia Therapeutics, Inc.Affinia Therapeutics, Inc.
08 Sep 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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