Delving into the Latest Updates on DN-024 with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

Target-

Mechanism-

Therapeutic Areas

Neoplasms

Active Indication

Solid tumor

Inactive Indication-

Originator Organization

Piistech

Active Organization

Piistech

Inactive Organization-

Drug Highest PhasePreclinical

First Approval Date-

Regulation-

A series of flavones and isoflavones were tested for their ability to inhibit reverse transcriptase of avian myeloblastosis virus (AMV).The inhibition of AMV reverse transcriptase was significant with quercetin, fisetin, myricetin or DN-24, whereas the effects of 7,8-hydroxyflavone, baicalein and morin were moderate.Apigenin, acacetin, DN-23, DN-25, genistein, biochanin A, D-(+)-catechin and α-naphthoflavone were of no or poor activity.Structure-activity relations are discussed.

100 Deals associated with DN-024

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