Last update 24 May 2025

NJH-05-043

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
NJH-05-043
Target
FGFR2
Action
antagonists
Mechanism
FGFR2 antagonists(Fibroblast growth factor receptor 2 antagonists)
Therapeutic Areas
NeoplasmsDigestive System DisordersOther Diseases
Active Indication
Bile Duct NeoplasmsStomach Cancer
Inactive Indication-
Originator Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Harvard Medical SchoolHarvard Medical School
Active Organization
Harvard Medical SchoolHarvard Medical SchoolDana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC52H64Cl2N12O8S
InChIKeyJTSBMXASQWEDHX-PRWMCYMISA-N
CAS Registry-

Related

100 Clinical Results associated with NJH-05-043
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100 Translational Medicine associated with NJH-05-043
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100 Patents (Medical) associated with NJH-05-043
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100 Deals associated with NJH-05-043
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bile Duct NeoplasmsPreclinical
United States
Harvard Medical SchoolHarvard Medical School
14 Jun 2021
Bile Duct NeoplasmsPreclinical
United States
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
14 Jun 2021
Stomach CancerPreclinical
United States
Harvard Medical SchoolHarvard Medical School
14 Jun 2021
Stomach CancerPreclinical
United States
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
14 Jun 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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