Last update 31 Jul 2025

LY-3885125

Overview

Basic Info

Drug Type
siRNA
Synonyms
SCAP siRNA, LY 3885125, LY3885125
Target
SCAP
Action
modulators
Mechanism
SCAP modulators(SREBF chaperone modulators)
Therapeutic Areas
Digestive System DisordersEndocrinology and Metabolic Disease
Active Indication-
Inactive Indication
DyslipidemiasMetabolic dysfunction-associated steatotic liver disease
Originator Organization
Eli Lilly & Co.Eli Lilly & Co.
Active Organization-
Inactive Organization
Eli Lilly & Co.Eli Lilly & Co.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with LY-3885125
NCT06007651
/ TerminatedPhase 1
A Phase 1, Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial of LY3885125 to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Ascending Dose in Participants With Dyslipidemia and Repeat-Doses in Participants With NAFLD
100 Clinical Results associated with LY-3885125
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100 Translational Medicine associated with LY-3885125
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100 Patents (Medical) associated with LY-3885125
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100 Deals associated with LY-3885125
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
DyslipidemiasPhase 1
United States
Eli Lilly & Co.Eli Lilly & Co.
10 Aug 2023
Metabolic dysfunction-associated steatotic liver diseasePhase 1
United States
Eli Lilly & Co.Eli Lilly & Co.
10 Aug 2023
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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