Last update 16 Apr 2025

THAL-NVP-2-02-099

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
THAL-NVP-2-02-099
Target
CDK9
Action
inhibitors
Mechanism
CDK9 inhibitors(Cyclin-dependent kinase 9 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Neoplasms
Originator Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Harvard Medical SchoolHarvard Medical School
Active Organization-
Inactive Organization
ActivX Biosciences, Inc.Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.Harvard Medical SchoolHarvard Medical School
+ [1]
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC46H57ClN10O9
InChIKeyJNHULBNMCUQKGV-JZSUORBJSA-N
CAS Registry-

Related

100 Clinical Results associated with THAL-NVP-2-02-099
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100 Translational Medicine associated with THAL-NVP-2-02-099
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100 Patents (Medical) associated with THAL-NVP-2-02-099
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100 Deals associated with THAL-NVP-2-02-099
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
Harvard Medical SchoolHarvard Medical School
18 Dec 2017
NeoplasmsPreclinical
United States
Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.
18 Dec 2017
NeoplasmsPreclinical
United States
ActivX Biosciences, Inc.
18 Dec 2017
NeoplasmsPreclinical
United States
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
18 Dec 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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