Last update 20 Nov 2025

1ST-104

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1ST 104, 1ST-104
Target
ABL1 x LRRK2
Action
modulators
Mechanism
ABL1 modulators(ABL proto-oncogene 1 modulators), LRRK2 modulators(Leucine-rich repeat serine/threonine-protein kinase 2 modulators)
Therapeutic Areas
Nervous System DiseasesEndocrinology and Metabolic Disease
Active Indication
Parkinson Disease
Inactive Indication
Amyotrophic Lateral SclerosisOlivopontocerebellar Atrophies
Originator Organization
1st Biotherapeutics, Inc.1st Biotherapeutics, Inc.
Active Organization
1st Biotherapeutics, Inc.1st Biotherapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhaseDiscovery
First Approval Date-
Regulation-

Related

100 Clinical Results associated with 1ST-104
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100 Translational Medicine associated with 1ST-104
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100 Patents (Medical) associated with 1ST-104
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100 Deals associated with 1ST-104
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Parkinson DiseaseDiscovery
South Korea
1st Biotherapeutics, Inc.1st Biotherapeutics, Inc.
01 May 2025
Amyotrophic Lateral SclerosisDiscovery
South Korea
1st Biotherapeutics, Inc.1st Biotherapeutics, Inc.
-
Olivopontocerebellar AtrophiesDiscovery
South Korea
1st Biotherapeutics, Inc.1st Biotherapeutics, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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