Last update 24 Feb 2025

CMD011

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
CMD 011, CMD-011, CMD011
Target
CD3
Mechanism
CD3 stimulants(T cell surface glycoprotein CD3 stimulants), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects), T lymphocytes stimulants
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication
Advanced Hepatocellular Carcinoma
Inactive Indication-
Originator Organization
Zhejiang Shimai Pharmaceutical Co., Ltd.Zhejiang Shimai Pharmaceutical Co., Ltd.
Active Organization
Zhejiang Shimai Pharmaceutical Co., Ltd.Zhejiang Shimai Pharmaceutical Co., Ltd.
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with CMD011
ChiCTR2300078740
/ RecruitingPhase 1/2IIT
A single-arm, open label, multicenter Phase I/IIa study evaluating the safety, tolerability, pharmacokinetic, and efficacy of CMD011 in patients with advanced hepatocellular carcinoma
CTR20233880
/ RecruitingPhase 1/2
一项评估CMD011在晚期肝细胞癌患者中安全性、耐受性、药代动力学特征和有效性的单臂、开放性、多中心的I/IIa期临床研究
[Translation] A single-arm, open-label, multicenter Phase I/IIa clinical study to evaluate the safety, tolerability, pharmacokinetic characteristics and efficacy of CMD011 in patients with advanced hepatocellular carcinoma
100 Clinical Results associated with CMD011
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100 Translational Medicine associated with CMD011
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100 Patents (Medical) associated with CMD011
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100 Deals associated with CMD011
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Hepatocellular CarcinomaPhase 2
CN
Zhejiang Shimai Pharmaceutical Co., Ltd.Zhejiang Shimai Pharmaceutical Co., Ltd.
08 Dec 2023
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Clinical Result

Indication
Phase
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Approval

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Regulation

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