Delving into the Latest Updates on Anti-PD1 Antibody-activated TILs(Sun Yat-sen University) with Synapse

Overview

Basic Info

Drug Type

TIL therapy

Synonyms-

Target

PD-1

Action

inhibitors

Mechanism

PD-1 inhibitors(Programmed cell death protein 1 inhibitors), Cell replacements

Therapeutic Areas-

Active Indication-

Inactive Indication-

Originator Organization

Sun Yat-Sen University

Active Organization-

Inactive Organization

Sun Yat-Sen University

License Organization-

Drug Highest PhasePendingPhase 1/2

First Approval Date-

Regulation-

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This study was a phase I/II trial initiated by the investigator to evaluate the safety and tolerability of anti-PD-1 antibody-activated TILs combined with adjuvant chemotherapy in participants with stage II-IIIA non-small cell lung cancer. 20 participants were enrolled and anti-PD-1 antibody-activated TILs was infused into participants after the final cycle chemotherapy to assess the safety and disease-free survival.

Start Date19 Feb 2019

Sponsor / Collaborator

Sun Yat-Sen University

NCT03904537

/ Unknown statusPhase 1/2IIT

A Phase I/II Study of Combination of Anti-Programmed Cell Death Protein 1(Anti-PD1) Antibody-activated Autologous Tumor Infiltrating Lymphocytes (TILs) and Chemotherapy in the Treatment of Stage III Colorectal Cancer.

This study was a phase I/II trial initiated by the investigator to evaluate the safety and tolerability of anti-programmed cell death protein 1 (anti-PD1) antibody-activated autologous tumor-infiltrating lymphocytes (TILs) combined with adjuvant chemotherapy in participants with stage III colon cancer. Twenty participants were enrolled and anti-PD1 antibody-activated TILs was infused into participants after the final of adjuvant chemotherapy to assess the safety and 3-year disease-free survival.

Start Date19 Feb 2019

Sponsor / Collaborator

Sun Yat-Sen University

100 Clinical Results associated with Anti-PD1 Antibody-activated TILs(Sun Yat-sen University)

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100 Translational Medicine associated with Anti-PD1 Antibody-activated TILs(Sun Yat-sen University)

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100 Patents (Medical) associated with Anti-PD1 Antibody-activated TILs(Sun Yat-sen University)

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100 Deals associated with Anti-PD1 Antibody-activated TILs(Sun Yat-sen University)

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