Last update 01 Nov 2025

[212Pb]Pb-PSV359

Overview

Basic Info

Drug Type
Radionuclide Drug Conjugates (RDC), Therapeutic radiopharmaceuticals, Peptide drug conjugates
Synonyms-
Target
FAP
Action
modulators
Mechanism
FAP modulators(Fibroblast activation protein alpha modulators)
Therapeutic Areas
NeoplasmsCongenital DisordersDigestive System Disorders+ [3]
Active Indication
Adenomatous Polyposis ColiEsophageal CarcinomaMesothelioma+ [4]
Inactive Indication-
Originator Organization
Perspective Therapeutics, Inc.
Active Organization
Perspective Therapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Structure/Sequence

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Related

1
Clinical Trials associated with [212Pb]Pb-PSV359
NCT06710756
/ RecruitingPhase 1/2
A Phase I/IIa Image-Guided, Alpha-Particle Therapy Study of [203Pb]Pb-PSV359 and [212Pb]Pb-PSV359 in Patients With Solid Tumors That Are Known to be Fibroblast Activation Protein (FAP)-Positive
100 Clinical Results associated with [212Pb]Pb-PSV359
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100 Translational Medicine associated with [212Pb]Pb-PSV359
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100 Patents (Medical) associated with [212Pb]Pb-PSV359
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100 Deals associated with [212Pb]Pb-PSV359
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Adenomatous Polyposis ColiPhase 2
United States
Perspective Therapeutics, Inc.
28 Apr 2025
Esophageal CarcinomaPhase 2
United States
Perspective Therapeutics, Inc.
28 Apr 2025
MesotheliomaPhase 2
United States
Perspective Therapeutics, Inc.
28 Apr 2025
Ovarian CancerPhase 2
United States
Perspective Therapeutics, Inc.
28 Apr 2025
Pancreatic Ductal AdenocarcinomaPhase 2
United States
Perspective Therapeutics, Inc.
28 Apr 2025
SarcomaPhase 2
United States
Perspective Therapeutics, Inc.
28 Apr 2025
Stomach CancerPhase 2
United States
Perspective Therapeutics, Inc.
28 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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