Last update 18 Oct 2025

DC-371739

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DC 371739
Target
PCSK9
Action
inhibitors
Mechanism
PCSK9 inhibitors(Proprotein convertase subtilisin kexin type 9 inhibitors)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication-
Inactive Indication
Hypercholesterolemia
Originator Organization
Shanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of Sci
Active Organization-
Inactive Organization
Shanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of SciGuangzhou Jiayue Pharmaceutical Technology Co., Ltd.Guangzhou Jiayue Pharmaceutical Technology Co., Ltd.
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with DC-371739
NCT04927221
/ CompletedPhase 1
A Randomized, Double-Blind, Placebo-Controlled Phase Ib/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DC739 Multiple-Dose in Hypercholesterolemic Subjects.
NCT04640012
/ CompletedPhase 1
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Ascending-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics of DC371739 Single-Dose Treatment in Healthy Subjects
100 Clinical Results associated with DC-371739
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100 Translational Medicine associated with DC-371739
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100 Patents (Medical) associated with DC-371739
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100 Deals associated with DC-371739
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HypercholesterolemiaPhase 1
China
Guangzhou Jiayue Pharmaceutical Technology Co., Ltd.Guangzhou Jiayue Pharmaceutical Technology Co., Ltd.
18 Sep 2020
HypercholesterolemiaPhase 1
China
Shanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of Sci
18 Sep 2020
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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