Last update 15 Nov 2025

Elbasvir/Grazoprevir Hydrate/Uprifosbuvir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Elbasvir/grazoprevir/MK-3682, Elbasvir/grazoprevir/uprifosbuvir, MK 3682/MK 8742/MK 5172
+ [2]
Target
NS3/NS4A x NS5A x NS5B polymerase
Action
inhibitors
Mechanism
NS3/NS4A inhibitors(Hepatitis C virus serine protease, NS3/NS4A inhibitors), NS5A inhibitors(Nonstructural protein 5A inhibitors), NS5B polymerase inhibitors(Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors)
Therapeutic Areas
Infectious DiseasesDigestive System Disorders
Active Indication-
Inactive Indication
Hepatitis C
Originator Organization
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
Active Organization-
Inactive Organization
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC49H55N9O7
InChIKeyBVAZQCUMNICBAQ-PZHYSIFUSA-N
CAS Registry1370468-36-2
View All Structures (3)

Related

100 Clinical Results associated with Elbasvir/Grazoprevir Hydrate/Uprifosbuvir
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100 Translational Medicine associated with Elbasvir/Grazoprevir Hydrate/Uprifosbuvir
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100 Patents (Medical) associated with Elbasvir/Grazoprevir Hydrate/Uprifosbuvir
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100 Deals associated with Elbasvir/Grazoprevir Hydrate/Uprifosbuvir
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis CPhase 2-
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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