Delving into the Latest Updates on CG101 with Synapse

Overview

Basic Info

Drug Type

Bispecific antibody

Synonyms

Target-

Action-

Mechanism-

Therapeutic Areas

Immune System Diseases

Active Indication

Autoimmune Diseases

Inactive Indication-

Originator Organization

Shanghai Kangjing Biomedical Technology Co., Ltd.

Active Organization

Shanghai Kangjing Biomedical Technology Co., Ltd.

Inactive Organization-

License Organization-

Drug Highest PhaseDiscovery

First Approval Date-

Regulation-

Author: Goossens, H. ; Fiett, J. ; Izdebski, R. ; Lerman, Y. ; Brun-Buisson, C. ; Sadowy, E. ; Baraniak, A. ; Vidal Samso, J. ; Lawrence, C. ; Malhotra-Kumar, S. ; Adler, A. ; Hryniewicz, W. ; Kazma, M. ; Fierro, J. ; Carmeli, Y. ; Salvia, A. ; Gniadkowski, M. ; Lammens, C. ; Salomon, J. ; Paul, M. ; Rossini, A.

ABSTRACT The international project MOSAR was conducted in five rehabilitation centers; patients were screened for rectal carriage of extended-spectrum β-lactamase (ESBL)-producing members of the Enterobacteriaceae . Among 229 Klebsiella pneumoniae isolates, four clonal groups (CG) or complexes (CC) prevailed: CG17 in France, CG101 in Italy, CG15 in Spain, and CC147 in Israel. ESBLs, mainly CTX-Ms, were produced by 226 isolates; three isolates expressed AmpC-like cephalosporinases. High genetic diversity of K. pneumoniae populations was observed, with specific characteristics at each center.

100 Deals associated with CG101

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R&D Status

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Indication	Highest Phase	Country/Location	Organization	Date
Autoimmune Diseases	Discovery	China	Shanghai Kangjing Biomedical Technology Co., Ltd.	15 Jul 2022

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Biosimilar

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