Last update 14 Oct 2025

GSK-5458514

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
PSMA Targeting T Cell Engager(GSK), GSK5458514
Target-
Action-
Mechanism-
Therapeutic Areas
NeoplasmsUrogenital Diseases
Active Indication
Metastatic castration-resistant prostate cancer
Inactive Indication-
Originator Organization
GSK PlcGSK Plc
Active Organization
GSK PlcGSK Plc
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
Login to view timeline

Related

1
Clinical Trials associated with GSK-5458514
NCT06990880
/ RecruitingPhase 1/2
A Phase 1/2 First-Time-In-Human, Open-Label, Multicenter, Dose Escalation and Expansion Study of GSK5458514 PSMA Targeting T Cell Engager Alone or in Combination With Other Anti-Cancer Agents in Adult Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
100 Clinical Results associated with GSK-5458514
Login to view more data
100 Translational Medicine associated with GSK-5458514
Login to view more data
100 Patents (Medical) associated with GSK-5458514
Login to view more data
100 Deals associated with GSK-5458514
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic castration-resistant prostate cancerPhase 2
United States
GSK PlcGSK Plc
12 Jun 2025
Metastatic castration-resistant prostate cancerPhase 2
Japan
GSK PlcGSK Plc
12 Jun 2025
Metastatic castration-resistant prostate cancerPhase 2
Canada
GSK PlcGSK Plc
12 Jun 2025
Metastatic castration-resistant prostate cancerPhase 2
United Kingdom
GSK PlcGSK Plc
12 Jun 2025
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free