Last update 01 Nov 2024

Insulin mouth rinse(Eastgate Biotech Corp.)

Last update 01 Nov 2024

Overview

R&D Status

Clinical Result

Translational Medicine

Overview

Basic Info

Drug Type

Hormone

Synonyms

Insugin, Insulin mouth rinse, Liquid insulin mouth rinse

Target

INSR

Mechanism

INSR agonists(Insulin receptor agonists)

Therapeutic Areas

Endocrinology and Metabolic DiseaseNervous System Diseases

Active Indication

Diabetes Mellitus, Type 2Alzheimer Disease

Inactive Indication

Diabetes Mellitus, Type 1

Originator Organization

Eastgate Biotech Corp.

Active Organization

Eastgate Biotech Corp.

Inactive Organization-

Drug Highest PhasePhase 3

First Approval Date-

Regulation-

Clinical Trials associated with Insulin mouth rinse(Eastgate Biotech Corp.)

DRKS00031913 / RecruitingNot ApplicableIIT

The additional use of a mouth wash with hydroxyapatite for the prevention of gingival diseases. - HAP-mouth wash for prevention of gingival diseases.

Start Date07 Jun 2023

Sponsor / Collaborator-

100 Clinical Results associated with Insulin mouth rinse(Eastgate Biotech Corp.)

100 Translational Medicine associated with Insulin mouth rinse(Eastgate Biotech Corp.)

100 Patents (Medical) associated with Insulin mouth rinse(Eastgate Biotech Corp.)

Literatures (Medical) associated with Insulin mouth rinse(Eastgate Biotech Corp.)

01 Aug 2007·American Journal of Orthodontics and Dentofacial OrthopedicsQ2 · MEDICINE

Caries preventive measures used in orthodontic practices: An evidence-based decision?

Q2 · MEDICINE

Article

Author: Anne Marie Kuijpers-Jagtman ; Jo E. Frencken ; Aniek Derks ; Martin A. Van’t Hof ; Christos Katsaros

INTRODUCTIONAlthough it is well known that treatment with fixed appliances increases the risk of enamel demineralization, little information is available about preventive measures that orthodontists actually use. This study was executed to survey measures used in orthodontic practices to prevent decalcifications during fixed appliance treatment, and to compare these measures with the available evidence-based information.METHODSA questionnaire was sent to all privately practicing orthodontists in the Netherlands who were affiliated with the Dutch Dental Association.RESULTSOf 229 orthodontists, 178 (78%) returned the questionnaires. Most of the orthodontists had a basic practice protocol for preventing demineralizations at the start of treatment. This protocol nearly always included oral hygiene instructions. If demineralizations occurred, 99% of the orthodontists took extra measures. Comparing the measures applied in the orthodontic practices with the evidence from a systematic review, a number of differences became apparent. The additional use of chlorhexidine or toothpaste with a high fluoride concentration (which has been demonstrated to have an inhibitive effect) is rarely prescribed. Fluoride rinse is prescribed most often, although there is not any high-quality, long-term study that demonstrates a caries preventive effect in orthodontic patients. Sixty-eight percent of the orthodontists considered it necessary to develop a practice guideline for preventing demineralizations.CONCLUSIONSOrthodontists do not implement the available evidence in order to prevent enamel demineralizations during fixed-appliance treatment. A practice guideline incorporating this information should be developed.

100 Deals associated with Insulin mouth rinse(Eastgate Biotech Corp.)

External Link

KEGG	Wiki	ATC	Drug Bank
-	-	A10AF01 A10AD01 A10AC01 A10AB01 A10AE01	-

R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Diabetes Mellitus, Type 2	Phase 3	-	Eastgate Biotech Corp.	-
Diabetes Mellitus, Type 1	Phase 2	PK	Eastgate Biotech Corp.	15 Apr 2019
Alzheimer Disease	Phase 2	PK	-	20 Jul 2018

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Insulin mouth rinse(Eastgate Biotech Corp.)

Overview

Basic Info

Related

External Link

R&D Status

Clinical Result

Translational Medicine

Deal

Core Patent

Clinical Trial

Approval

Regulation