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Clinical Trials associated with Positive Skin Test Control-HistamineImmunologic Profile of Chronically Photodamaged Skin
Chronically photodamaged skin is visually characterized by dryness, wrinkles, brown spots, leathery appearance, etc. This happens as a result of excessive exposure to UV light from the sun. While the sun's exposure leaves the skin's surface visibly changed, the skin's unseen immune system may also be permanently altered as a result of the exposure, making it more likely to develop a variety of skin cancers and infections. This study will examine the lasting changes in the immune system of the skin caused by UV exposure. Investigators will stimulate different aspects of the skin's immune system by giving an injection of Candida Albicans (CANDIN®) and histamine phosphate (HISTATROL®), topical applications of imiquimod 5% cream (ALDARA®) and performing a tape stripping procedure with adhesive tape. The use of Candida Albicans (CANDIN®), histamine phosphate (HISTATROL®), and tape stripping are common procedures in clinical settings to stimulate skin desired skin responses. Imiquimod 5% cream (ALDARA®) is an FDA-approved drug for the treatment of basal cell carcinomas, actinic keratoses and genital warts. Investigators will compare the reaction of the skin's immune system on a cellular level from skin normally exposed to the sun exposure to an area normally hidden from sun exposure.
The Impact of a 3-day High-altitude Mountain Trek on the Emotional States of Children
The mood was influenced by many factors in children. Sport, such as high-altitude mountain trek activity was thought benefit for human's mood and health. The expedition therapy was more and more popular in many schools recently. However, as the investigators best knowledge, there was no article discuss the relation between the mood and high-altitude mountain trek activity such as benefit influence in children. So, the investigators conduct the study.
Method: Demographic data will be recorded. The Professor Yeh's mood questionnaires were used to record the mood status of before and after the 3 days high-altitude mountain trek activity.
Statistical analyses: Participants rated their emotional states (happiness, sadness, anticipation, and anger) on a Likert scale. Each variable will be presented as descriptive statistics. Student t test or other suitable statistical method(s) will be used to determine the correction among the variables with scores of mood status. The paired t test or other suitable statistical method(s) will be used to determine the correction among the scores of mood status before and after the mountain activity. A difference was considered statistically significant if the p value were less than 0.05. All statistical analyses will be performed using SPPS statistical software for Windows, version 14 or more updated version.
A Dose-Escalating Phase 0 Study to Evaluate the Safety and Local Cutaneous Reactivity of Intradermal Human Fcγ1-Fel d1 Fusion Protein (GFD) in Cat-allergic Healthy Volunteers
The purpose of this trial is to show that Intradermal Human Fcγ1-Fel d1 fusion protein (GFD) is able to block the skin reaction to cat allergen in cat allergic subjects compared to the skin reaction to cat allergen alone. This research project is also testing the safety and tolerability of this new, experimental treatment, compared to the current treatment of cat allergen alone.
100 Clinical Results associated with Positive Skin Test Control-Histamine
100 Translational Medicine associated with Positive Skin Test Control-Histamine
100 Patents (Medical) associated with Positive Skin Test Control-Histamine
100 Deals associated with Positive Skin Test Control-Histamine