[Translation] A phase IIa, randomized, double-blind, placebo-controlled, dose-finding study of JMKX000189 in the treatment of moderately to severely active systemic lupus erythematosus
主要目的
评价JMKX000189片在中重度活动性SLE受试者中的药效学(PD)特征
次要目的
评价JMKX000189片在中重度活动性SLE受试者中降低疾病活动度的疗效
评价JMKX000189片在中重度活动性SLE受试者中的安全性和耐受性
评价JMKX000189片在中重度活动性SLE受试者中的药代动力学(PK)特征
[Translation] Primary objective
To evaluate the pharmacodynamic (PD) characteristics of JMKX000189 tablets in subjects with moderately to severely active SLE
Secondary objectives
To evaluate the efficacy of JMKX000189 tablets in reducing disease activity in subjects with moderately to severely active SLE
To evaluate the safety and tolerability of JMKX000189 tablets in subjects with moderately to severely active SLE
To evaluate the pharmacokinetic (PK) characteristics of JMKX000189 tablets in subjects with moderately to severely active SLE