Last update 28 Mar 2026

GB-4558

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Atopic Dermatitis(Generate Biomedicines), GB 4558, GB-4558
+ [1]
Target
OX40L
Action
inhibitors
Mechanism
OX40L inhibitors(Tumor necrosis factor ligand superfamily member 4 inhibitors)
Therapeutic Areas
Immune System DiseasesCongenital DisordersSkin and Musculoskeletal Diseases
Active Indication-
Inactive Indication
Dermatitis, Atopic
Originator Organization
Generate Biomedicines, Inc.Generate Biomedicines, Inc.
Active Organization-
Inactive Organization
Generate Biomedicines, Inc.Generate Biomedicines, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with GB-4558
Login to view more data
100 Translational Medicine associated with GB-4558
Login to view more data
100 Patents (Medical) associated with GB-4558
Login to view more data
100 Deals associated with GB-4558
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Dermatitis, AtopicPreclinical
United States
Generate Biomedicines, Inc.Generate Biomedicines, Inc.
05 Sep 2024
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
login
or
view full example data
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free