Last update 08 May 2025

3A11-vc-MMAE

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
Target
FGFR4 x Tubulin
Action
antagonists, inhibitors
Mechanism
FGFR4 antagonists(Fibroblast growth factor receptor 4 antagonists), Tubulin inhibitors
Therapeutic Areas
NeoplasmsOther Diseases
Active Indication
Rhabdomyosarcoma
Inactive Indication-
Originator Organization
Manhattan BioSolutions, Inc.Manhattan BioSolutions, Inc.
Active Organization
Manhattan BioSolutions, Inc.Manhattan BioSolutions, Inc.
National Cancer InstituteNational Cancer Institute
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC11H22N4O4
InChIKeyAGGWFDNPHKLBBV-YUMQZZPRSA-N
CAS Registry159858-33-0
View All Structures (2)
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Related

100 Clinical Results associated with 3A11-vc-MMAE
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100 Translational Medicine associated with 3A11-vc-MMAE
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100 Patents (Medical) associated with 3A11-vc-MMAE
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100 Deals associated with 3A11-vc-MMAE
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
RhabdomyosarcomaPreclinical
United States
National Cancer InstituteNational Cancer Institute
05 Apr 2024
RhabdomyosarcomaPreclinical
United States
Manhattan BioSolutions, Inc.Manhattan BioSolutions, Inc.
05 Apr 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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