Last update 23 Jan 2025

GDC-18

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
Target
GPX4
Mechanism
GPX4 degraders(glutathione peroxidase 4 degraders)
Therapeutic Areas
Neoplasms
Active Indication
Neoplasms
Inactive Indication-
Originator Organization
Zhejiang Chinese Medical UniversityZhejiang Chinese Medical University
Active Organization
Zhejiang Chinese Medical UniversityZhejiang Chinese Medical University
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC43H46ClN7O8S
InChIKeyLGASPVUKBCDRLN-UHFFFAOYSA-N
CAS Registry2922747-81-5

Related

100 Clinical Results associated with GDC-18
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100 Translational Medicine associated with GDC-18
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100 Patents (Medical) associated with GDC-18
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100 Deals associated with GDC-18
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
CN
Zhejiang Chinese Medical UniversityZhejiang Chinese Medical University
26 May 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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