Last update 10 Nov 2025

Selective CBP(Foghorn Therapeutics)

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
CBPd-171
Target
CREBBP x EP300
Action
degraders
Mechanism
CREBBP degraders(cAMP-response element binding protein degraders), EP300 degraders(Histone acetyltransferase p300 degraders)
Therapeutic Areas
NeoplasmsDigestive System DisordersSkin and Musculoskeletal Diseases+ [4]
Active Indication
Breast CancerStomach CancerBladder Cancer+ [4]
Inactive Indication-
Originator Organization
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
Active Organization
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with Selective CBP(Foghorn Therapeutics)
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100 Translational Medicine associated with Selective CBP(Foghorn Therapeutics)
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100 Patents (Medical) associated with Selective CBP(Foghorn Therapeutics)
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100 Deals associated with Selective CBP(Foghorn Therapeutics)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Breast CancerPreclinical
United States
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
13 Jun 2024
Stomach CancerPreclinical
United States
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
13 Jun 2024
Bladder CancerDiscovery
United States
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
17 Apr 2024
Colorectal CancerDiscovery
United States
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
17 Apr 2024
Diffuse Large B-Cell LymphomaDiscovery
United States
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
17 Apr 2024
Endometrial CarcinomaDiscovery
United States
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
17 Apr 2024
Non-Small Cell Lung CancerDiscovery
United States
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
17 Apr 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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