Last update 28 Feb 2026

8R-70CAR T cells(Defense Language Institute Foreign Language Center)

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
x-Vivo expanded autologous IL-8 receptor (CXCR2) modified CD70 CAR (8R-70CAR) T cells
Target
CD70
Action
modulators
Mechanism
CD70 modulators(CD70 antigen modulators)
Therapeutic Areas
NeoplasmsNervous System DiseasesOther Diseases
Active Indication
High grade gliomaCD70 positive NeoplasmsGlioblastoma Multiforme
Inactive Indication-
Originator Organization
Defense Language Institute Foreign Language CenterDefense Language Institute Foreign Language Center
Active Organization
University of FloridaUniversity of Florida
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
Login to view timeline

Related

1
Clinical Trials associated with 8R-70CAR T cells(Defense Language Institute Foreign Language Center)
NCT05353530
/ RecruitingPhase 1IIT
Phase I Study -To Assess Safety and Feasibility of IL-8 Receptor Modified Patient-derived Activated CD70 CAR T Cell Therapy in CD70+ Adult GBM and Pediatric High-Grade Gliomas (pHGG)
100 Clinical Results associated with 8R-70CAR T cells(Defense Language Institute Foreign Language Center)
Login to view more data
100 Translational Medicine associated with 8R-70CAR T cells(Defense Language Institute Foreign Language Center)
Login to view more data
100 Patents (Medical) associated with 8R-70CAR T cells(Defense Language Institute Foreign Language Center)
Login to view more data
100 Deals associated with 8R-70CAR T cells(Defense Language Institute Foreign Language Center)
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
High grade gliomaPhase 1
United States
University of FloridaUniversity of Florida
18 Mar 2025
CD70 positive NeoplasmsPhase 1
United States
University of FloridaUniversity of Florida
25 Jul 2023
Glioblastoma MultiformePhase 1
United States
University of FloridaUniversity of Florida
25 Jul 2023
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free