Last update 08 May 2025

PAC-113

Overview

Basic Info

Drug Type
Recombinant polypeptide
Synonyms
+ [1]
Target
Reactive oxygen species
Action
stimulants, enhancers
Mechanism
Reactive oxygen species stimulants, Cell membrane permeability enhancers
Therapeutic Areas
Infectious DiseasesMouth and Tooth Diseases
Active Indication
Candidiasis, Oral
Inactive Indication
GingivitisMucositis
Originator Organization
Demegen, Inc.Demegen, Inc.
Active Organization
Demegen, Inc.Demegen, Inc.
Inactive Organization
Pacgen Life Science Corp.Pacgen Life Science Corp.
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with PAC-113
NCT00659971
/ CompletedPhase 2
A Phase 2B Dose-Ranging Study of PAC113 Mouthrinse for Clinical and Microbial Evaluation in HIV Seropositive Individuals With Oral Candidiasis to Establish the Optimal Dose of PAC113
100 Clinical Results associated with PAC-113
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100 Translational Medicine associated with PAC-113
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100 Patents (Medical) associated with PAC-113
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100 Deals associated with PAC-113
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External Link

KEGGWikiATCDrug Bank
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DB05756

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Candidiasis, OralPhase 2-
Demegen, Inc.Demegen, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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