Last update 21 Nov 2024

1045U85

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
5-HT receptor x ADRA1 x β1-adrenergic receptor
Mechanism
5-HT receptor antagonists(Serotonin (5-HT) receptor antagonists), ADRA1 antagonists(Adrenergic receptor alpha-1 antagonists), β1-adrenergic receptor antagonists(Beta-1 adrenergic receptor antagonists)
Therapeutic Areas
Cardiovascular Diseases
Active Indication-
Inactive Indication
Hypertension
Originator Organization
GSK PlcGSK Plc
Active Organization-
Inactive Organization
GSK PlcGSK Plc
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
Login to view timeline

Structure

Molecular FormulaC20H25ClN2O4S
InChIKeyLJMRDNZQKNDDBY-UHFFFAOYSA-N
CAS Registry129280-22-4
View All Structures (2)

Related

100 Clinical Results associated with 1045U85
Login to view more data
100 Translational Medicine associated with 1045U85
Login to view more data
100 Patents (Medical) associated with 1045U85
Login to view more data
1
Literatures (Medical) associated with 1045U85
01 Nov 1994Journal of Pharmaceutical and Biomedical AnalysisQ3 · MEDICINE
Development and validation of a chiral LC method for analysis of the four stereoisomers of 1045U85 in plasma
Q3 · MEDICINE
100 Deals associated with 1045U85
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
HypertensionPhase 1
GB
GSK PlcGSK Plc
-
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free