Last update 11 Mar 2026

BMS-645737

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
BMS-645737
Target
FGFR1 x VEGFR2
Action
antagonists
Mechanism
FGFR1 antagonists(Fibroblast growth factor receptor 1 antagonists), VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Neoplasms
Originator Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Active Organization-
Inactive Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
License Organization-
Drug Highest PhasePendingDiscovery
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC20H20N8O
InChIKeyOOQXPATWSOGSAV-UHFFFAOYSA-N
CAS Registry651744-16-0

Related

100 Clinical Results associated with BMS-645737
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100 Translational Medicine associated with BMS-645737
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100 Patents (Medical) associated with BMS-645737
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1
Literatures (Medical) associated with BMS-645737
01 May 2008Bioorganic & medicinal chemistry lettersQ4 · MEDICINE
Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor
Q4 · MEDICINE
100 Deals associated with BMS-645737
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsDiscovery
United States
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
-
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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