Last update 14 Dec 2024

TFX05-01

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
TFX05 01, TFX05-01, TFX0501
Target
17β-HSD5
Mechanism
17β-HSD5 inhibitors(Aldo-keto-reductase family 1 member C3 inhibitors)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Advanced cancerAdvanced Malignant Solid NeoplasmHematologic Neoplasms+ [1]
Inactive Indication-
Originator Organization
Shenzhen Yangli Pharmaceutical Technology Co. Ltd.Shenzhen Yangli Pharmaceutical Technology Co. Ltd.
Active Organization
Shenzhen Yangli Pharmaceutical Technology Co. Ltd.Shenzhen Yangli Pharmaceutical Technology Co. Ltd.WuXi AppTec (Shanghai) Co. Ltd.WuXi AppTec (Shanghai) Co. Ltd.
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with TFX05-01
CTR20220957 / RecruitingPhase 1
评估TFX05-01治疗晚期实体瘤受试者的安全性、耐受性、药代动力学、疗效以及与 AKR1C3酶表达相关性的临床研究。
[Translation] A clinical study to evaluate the safety, tolerability, pharmacokinetics, efficacy and correlation with AKR1C3 enzyme expression of TFX05-01 in the treatment of subjects with advanced solid tumors.
NCT05434299 / RecruitingPhase 1/2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of TFX05-01 in Participants With Advanced Malignancies
100 Clinical Results associated with TFX05-01
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100 Translational Medicine associated with TFX05-01
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100 Patents (Medical) associated with TFX05-01
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100 Deals associated with TFX05-01
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced cancerPhase 2
CN
Shenzhen Yangli Pharmaceutical Technology Co. Ltd.Shenzhen Yangli Pharmaceutical Technology Co. Ltd.
05 Jun 2022
Advanced Malignant Solid NeoplasmPhase 2
CN
Shenzhen Yangli Pharmaceutical Technology Co. Ltd.Shenzhen Yangli Pharmaceutical Technology Co. Ltd.
05 Jun 2022
Hematologic NeoplasmsIND Approval
CN
Shenzhen Yangli Pharmaceutical Technology Co. Ltd.Shenzhen Yangli Pharmaceutical Technology Co. Ltd.
14 Jul 2023
Solid tumorPreclinical
CN
WuXi AppTec (Shanghai) Co. Ltd.WuXi AppTec (Shanghai) Co. Ltd.
15 Jun 2022
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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