Last update 21 Nov 2024

RO-7616789

Overview

Basic Info

Drug Type
Trispecific T-cell engager (TriTE)
Synonyms
Target
4-1BB x CD3 x DLL3
Mechanism
4-1BB inhibitors(Tumor necrosis factor receptor superfamily member 9 inhibitors), CD3 modulators(T cell surface glycoprotein CD3 modulators), DLL3 inhibitors(Delta-like protein 3 inhibitors)
Therapeutic Areas
NeoplasmsRespiratory Diseases
Active Indication
Neuroendocrine CarcinomaSmall Cell Lung Cancer
Inactive Indication-
Originator Organization
F. Hoffmann-La Roche Ltd.
Active Organization
F. Hoffmann-La Roche Ltd.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with RO-7616789
NCT05619744 / RecruitingPhase 1
An Open-Label, Multicenter Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-Tumor Activity of RO7616789 in Participants With Advanced Small Cell Lung Cancer and Other Neuroendocrine Carcinomas
100 Clinical Results associated with RO-7616789
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100 Translational Medicine associated with RO-7616789
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100 Patents (Medical) associated with RO-7616789
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100 Deals associated with RO-7616789
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Neuroendocrine CarcinomaPhase 1
DK
F. Hoffmann-La Roche Ltd.
23 Jan 2023
Neuroendocrine CarcinomaPhase 1
US
F. Hoffmann-La Roche Ltd.
23 Jan 2023
Neuroendocrine CarcinomaPhase 1
JP
F. Hoffmann-La Roche Ltd.
23 Jan 2023
Neuroendocrine CarcinomaPhase 1
PL
F. Hoffmann-La Roche Ltd.
23 Jan 2023
Neuroendocrine CarcinomaPhase 1
ES
F. Hoffmann-La Roche Ltd.
23 Jan 2023
Small Cell Lung CancerPhase 1
PL
F. Hoffmann-La Roche Ltd.
23 Jan 2023
Small Cell Lung CancerPhase 1
US
F. Hoffmann-La Roche Ltd.
23 Jan 2023
Small Cell Lung CancerPhase 1
JP
F. Hoffmann-La Roche Ltd.
23 Jan 2023
Small Cell Lung CancerPhase 1
ES
F. Hoffmann-La Roche Ltd.
23 Jan 2023
Small Cell Lung CancerPhase 1
DK
F. Hoffmann-La Roche Ltd.
23 Jan 2023
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Clinical Result

Indication
Phase
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Approval

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Regulation

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