Last update 26 Aug 2025

APN-1701

Overview

Basic Info

Drug Type
Chemical drugs, Diagnostic radiopharmaceuticals
Synonyms
18F-AM-PBB3, APN 1701, [18F]AM-PBB3
Target
TAU
Action
inhibitors, enhancers
Mechanism
TAU inhibitors(Microtubule-associated protein tau inhibitors), PET imaging(Positron-emission tomography enhancers)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication
Alzheimer DiseaseNerve Degeneration
Inactive Indication-
Originator Organization
National Institute of Radiological SciencesNational Institute of Radiological Sciences
Active Organization
Aprinoia Therapeutics, Inc.Aprinoia Therapeutics, Inc.
National Institute of Radiological SciencesNational Institute of Radiological Sciences
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with APN-1701
JPRN-UMIN000029084
/ RecruitingNot Applicable
Investigation for efficacy and safety of tau PET ligand [18F]AM-PBB3 - Investigation for efficacy and safety of tau PET ligand [18F]AM-PBB3
JPRN-UMIN000020065
/ Unknown statusNot Applicable
Investigation for efficacy and safety of tau PET ligand [18F]AM-PBB3 - Investigation for efficacy and safety of tau PET ligand [18F]AM-PBB3
100 Clinical Results associated with APN-1701
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100 Translational Medicine associated with APN-1701
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100 Patents (Medical) associated with APN-1701
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100 Deals associated with APN-1701
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Alzheimer DiseasePhase 2-
Aprinoia Therapeutics, Inc.Aprinoia Therapeutics, Inc.
-
Alzheimer DiseasePhase 2-
National Institute of Radiological SciencesNational Institute of Radiological Sciences
-
Nerve DegenerationPhase 2-
Aprinoia Therapeutics, Inc.Aprinoia Therapeutics, Inc.
-
Nerve DegenerationPhase 2-
National Institute of Radiological SciencesNational Institute of Radiological Sciences
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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