Last update 20 Sep 2025

APH-0804

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
APH-0804
Target
TDP1 x Top I
Action
inhibitors
Mechanism
TDP1 inhibitors(tyrosyl-DNA phosphodiesterase 1 inhibitors), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication
Colonic CancerLung CancerOvarian Cancer
Inactive Indication-
Originator Organization
National Cancer InstituteNational Cancer Institute
Active Organization
Aphios Corp.Aphios Corp.
Inactive Organization
National Cancer InstituteNational Cancer Institute
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with APH-0804
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100 Translational Medicine associated with APH-0804
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100 Patents (Medical) associated with APH-0804
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100 Deals associated with APH-0804
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colonic CancerPreclinical
United States
Aphios Corp.Aphios Corp.
01 Sep 2025
Lung CancerPreclinical
United States
Aphios Corp.Aphios Corp.
01 Sep 2025
Ovarian CancerPreclinical
United States
Aphios Corp.Aphios Corp.
01 Sep 2025
NeoplasmsDiscovery
United States
National Cancer InstituteNational Cancer Institute
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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