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Calcium Laevulinate

Last update 08 May 2025

Overview

R&D Status

Clinical Result

Translational Medicine

Overview

Basic Info

Drug Type

Small molecule drug

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Mechanism

Calcium supplements

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Structure/Sequence

Molecular FormulaC10H16CaO6

InChIKeyHBDZVTRGNQBPEV-UHFFFAOYSA-N

CAS Registry591-64-0

100 Clinical Results associated with Calcium Laevulinate

100 Translational Medicine associated with Calcium Laevulinate

100 Patents (Medical) associated with Calcium Laevulinate

Literatures (Medical) associated with Calcium Laevulinate

27 Jan 2021·Industrial & Engineering Chemistry Research

Intensification of Biomass Thermal Deoxygenation via a Two-Stage Process

Author: Wheeler, M. Clayton ; Eaton, Scott J.

Thermal deoxygenation (TDO) is a promising reaction scheme for producing low oxygen bio-oil from biomass carbohydrate.The primary step in bio-oil production involves pyrolysis of alk. earth metal-neutralized biomass hydrolyzates at 723 K yielding bio-oil, chars, carbonates, and light gases.Reactor scaling from bench to floor-scale, however, reduced carbon yields from 80% to 48% of theor., resp.This paper details a two-stage process to intensify the TDO process, improving carbon yields to 79% of theor.The scheme involves a 523 K thermal pretreatment (stage I) to yield a polysalt and transition of a melt-phase.The resulting solid polysalt is reduced to powder to improve material handling and reaction rates during decomposition at 723 K (stage II).Resulting bio-oil yield is shown to improve from 0.082 to 0.16 kg-oil/kg-feed.A two-step reaction model is developed detailing the reaction rates and regimes which can guide continuous process design efforts.

01 Jan 2019·Materials Today: Proceedings

Straightforward synthesis of calcium levulinate from biomass-derived levulinic acid and calcium carbonate in egg-shells

Author: B.O. Sharath ; Sib Sankar Mal ; Saikat Dutta ; Ritesh Tiwari

Calcium levulinate (CL) is a nutritional supplement for calcium and a chem. intermediate in synthesizing levulinic biofuels.The reported synthesis of CL involve reaction between cellulose-derived levulinic acid (LA) and calcium hydroxide in an aqueous medium.In this work, we report the production of CL using CaCO₃ from poultry egg shells.The scalable production uses biomass-derived LA and egg-shell derived CaCO₃ under conventional heating and mech. stirring.The reaction was optimized on temperature, duration of reaction, and equivalent of CaCO₃.Using 1.5 equiv of CaCO₃, the reaction completed within 2h at 50°C and afforded up to 97% isolated yield of CL as a crystalline solid.The reaction was also successfully carried out under mech. grinding and scaled up to 20 g.The purity of the product was confirmed by m.p., FTIR, ¹H-NMR and ¹³C-NMR spectroscopy.

01 Dec 2018·Carbohydrate PolymersQ1 · CHEMISTRY

Versatile acid base sustainable solvent for fast extraction of various molecular weight chitin from lobster shell

Q1 · CHEMISTRY

Article

Author: Yuan, Yang ; Yang, Qiuru ; Zhu, Ping ; Lian, Hailan ; Hong, Shu

Deep eutectic solvent (DES) prepared from choline chloride and four organic acid were evaluated for the extraction of chitin from lobster shell. It was found that the purity of chitins extracted with DESs was related to acid used. Purity of chitin extracted with choline chloride-malonic acid was the highest. Chitins extracted through DES treatment results in various molecular weight, which is associated with type of acid and temperature used during the treatment. For instance, chitin produced by malonic acid at 50 °C and 100 °C results in molecular weight of 312 KDa and 199 KDa respectively, whereas it extracted with malic acid at 100 °C results in 91 KDa. The physicochemical properties of chitins were characterized by FTIR, XRD, TG and SEM. Moreover, the CaCO₃ was successfully converted into levulinic acid calcium salt which could be used as calcium supplement.

100 Deals associated with Calcium Laevulinate

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Calcium Laevulinate

Overview

Basic Info

Structure/Sequence

Related

R&D Status

Clinical Result

Translational Medicine

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Core Patent

Clinical Trial

Approval

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