Last update 18 Apr 2026

BMS-986484

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
CD40xFAP Bispecific (Bristol Myers Squibb), BMS 986484, BMS986484
Target
CD40 x FAP
Action
inhibitors, antagonists
Mechanism
CD40 inhibitors(Tumor necrosis factor receptor superfamily member 5 inhibitors), FAP antagonists(Fibroblast activation protein alpha antagonists)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Active Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with BMS-986484
NCT06544655
/ Active, not recruitingPhase 1
A Phase 1/1b First-in-human Trial of BMS-986484 as Monotherapy and Combination Therapy in Participants With Advanced Solid Malignancies
100 Clinical Results associated with BMS-986484
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100 Translational Medicine associated with BMS-986484
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100 Patents (Medical) associated with BMS-986484
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100 Deals associated with BMS-986484
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
United States
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
10 Oct 2024
Advanced Malignant Solid NeoplasmPhase 1
Australia
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
10 Oct 2024
Advanced Malignant Solid NeoplasmPhase 1
Canada
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
10 Oct 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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