Last update 08 May 2025

Alpha-1-antitrypsin gene therapy-inhalation(Generx+)

Overview

Basic Info

Drug Type
Gene therapy
Synonyms
Alpha-1-antitrypsin gene therapy-inhalation, Alphagen
Target
Trypsin
Action
inhibitors
Mechanism
Trypsin inhibitors
Therapeutic Areas
Congenital DisordersDigestive System DisordersRespiratory Diseases+ [1]
Active Indication-
Inactive Indication
Alpha 1-Antitrypsin DeficiencyPulmonary Disease, Chronic ObstructivePulmonary Emphysema
Originator Organization
Generx, Inc.
Active Organization-
Inactive Organization
Aradigm Corp.Aradigm Corp.Generx, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with Alpha-1-antitrypsin gene therapy-inhalation(Generx+)
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100 Translational Medicine associated with Alpha-1-antitrypsin gene therapy-inhalation(Generx+)
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100 Patents (Medical) associated with Alpha-1-antitrypsin gene therapy-inhalation(Generx+)
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100 Deals associated with Alpha-1-antitrypsin gene therapy-inhalation(Generx+)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Alpha 1-Antitrypsin DeficiencyPhase 1-
Aradigm Corp.Aradigm Corp.
-
Alpha 1-Antitrypsin DeficiencyPhase 1-
Generx, Inc.
-
Pulmonary Disease, Chronic ObstructivePhase 1-
Aradigm Corp.Aradigm Corp.
-
Pulmonary Disease, Chronic ObstructivePhase 1-
Generx, Inc.
-
Pulmonary EmphysemaPhase 1
United States
Aradigm Corp.Aradigm Corp.
-
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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